ANTIBACTERIAL, ANTIFUNGAL AND ANTIOXIDANT ACTIVITTES OF DERIVATIVES OF ALKYL PIPERIDINE

Authors

  • SARWAT JAHAN Federal Urdu University of Arts, Science and Technology, Gulshan-e-Iqbal, Karachi
  • SHAMIM AKHTAR Faculty of Pharmacy, University of Karachi,
  • ARFA KAMIL Faculty of Pharmacy, University of Karachi,
  • Z.S. SAIFY HEJ Research Institute of Chemistry, University of Karachi, Karachi-75270, Pakistan.
  • NOUSHEEN MUSHTAQ Faculty of Pharmacy, University of Karachi,
  • M. ARIF Faculty of Pharmacy, University of Karachi,

Abstract

Antibacterial, antifungal and antioxidant activities of alkyl piperidine derivatives have been reported. Derivatives of compound I (Ia- If) and compound II (IIa-IIf) were screened for antibacterial activity against several gram negative and gram-positive bacteria. The criterion of activity was the inhibition of growth of microorganisms i.e. zone of inhibition and it is measured in millimeter. It was found that all the derivatives displayed moderate to good antibacterial activity.

Author Biographies

SHAMIM AKHTAR, Faculty of Pharmacy, University of Karachi,

Department of Pharmaceutical Chemistry,

ARFA KAMIL, Faculty of Pharmacy, University of Karachi,

Department of Pharmaceutical Chemistry,

NOUSHEEN MUSHTAQ, Faculty of Pharmacy, University of Karachi,

Department of Pharmaceutical Chemistry,

M. ARIF, Faculty of Pharmacy, University of Karachi,

Department of Pharmaceutical Chemistry,

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Published

2012-06-15

Issue

Vol. 2 No. 1 june (2012): Fuuast Journal of Biology

Section

Articles