BIOACTIVIIES OF SCORZONERA PARADOXAFISCH & C.A. MEY. A MEDICINAL PLANT OF PUNJGUR, BALOCHISTAN, PAKISTAN
The present study is focused to determine antibacterial, antifungal, antileishmanial, cytotoxicity, phytotoxicity and insecticidal activity of medicinal plant Scorzonera paradoxa. The plant belongs to family Asteraceae collected from Punjgur, Balochistan. The plant is also studied for its ash and moisture content. Crude methanolic extract of the plant was tested against 10 bacterial and 08 fungal strains by using agar tube dilution method and agar well diffusion method respectively. Its toxicity is checked through Brine shrimp and Lemna aequinoctialis test using standard methods. The results shows 21% ash and 79% moisture content, the crude extract was significantly active against bacterial strain Salmonella typhi with 75% inhibition while it was inactive against other studied bacterial. Highly significant activity is observed against fungi Trichophyton schoenleinii, T.simii, Fusarium oxysporum and F.solani. Maximum inhibition 84% is achieved against Trichophyton schoenleini. Cytotoxicity and phytotoxicity are not observed.
Key words: Scorzonera paradoxa; Bioactivities; Antifungal; Panjgur, Balochisran.