ANTIBACTERIAL ACTIVITY OF HEXANE EXTRACT OF CORCHORUS DEPRESSES AGAINST STAPHYLOCOCCUS AUREUS, BACILLUS CEREUS, SALMONELLA TYPHI AND ESCHERICHIA COLI

Authors

  • AHMED SHAHID MIRZA Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • MIRZA TASAWER BAIG Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • AMBREEN HUMA Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • SADAF IBRAHIM Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • UZMA SHAHID Faculty of Medicine, Ziauddin University, Karachi Pakistan
  • AISHA JABEEN Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • MEHWISH MURAD ALI Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • RASHEEDA FATIMA Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • ADEEL ARSALAN Faculty of Pharmacy, Ziauddin University, Karachi Pakistan
  • SABA SHAIKH Faculty of Pharmacy, Ziauddin University, Karachi Pakistan

Abstract

Corchorus depressus is therapeutically active plant and successfully used in medicine. The purpose of this study was to determine the antibacterial activity of hexanolic extract of Corchorus depressus against four microorganism two gram positive (Staphylococcus aureus and Bacillus cereus) and two gram negative (Salmonella typhi and Escherichia coli). Antibacterial activity of Corchorus depressus leaves were assessed by disc diffusion method. Antibiotics; Cefixime (5?????), Cefriaxone (30 ?????), Ciprofloxacin (5 ?????) and Co-amoxiclav (30 ?????) were used to compare the Hexane extract of Corchorus depressus that exhibit good antibacterial activity against all four microorganisms. The results of inhibitory zones of Hexane extract of Corchorus depressus were high (26±1.6) as compared with Ciprofloxacin (23±5.7) against S. aureus. The results shown that the MICs of hexane extract of Corchorus depressus was recorded high against gram positive S.aureus (0.321±0.23) and gram negative S. typhi (0.26 ± 0.07). It was concluded that Corchorus depressusexhibited profound antibacterial activity against microbes.

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Published

2020-12-24