ANALYSIS OF DIGESTIVE DISORDERS DUE TO STATIN THERAPY IN HYPERCHOLESTRIMIA; A COHORT STUDY AMONG DIABETIC AND NON DIABETIC PATIENTS

Authors

  • KIRAN RAFIQ Jinnah Sindh Medical University, Karachi
  • ZAFAR SAIED SAIFY University of Karachi.

Abstract

Statins are cholesterol-lowering drugs, commonly prescribed for the significant decline of  high risks leading to  arrhythmia and other cardiac issues. A study conducted reveals that 40% of population among the patients of cardiovascular, got arterial fibrillation with statins and 80% without statins that are mostly prescribed along with antihypertensive and if patient is diabetic, a regime of medicine is given for the management of all probable disorders and that sometimes may lead to undesired effects specifically regarding gastric. The present study is conducted to focus the root cause of digestive disorders as either medicine or condition. In present study the method adopted was cohort study and for the purpose prescription and history of case and control groups that were both hypercholestrimic and hypertensive but diabetic and non diabetic respectively. The study out comes reveal that 67% of case group reported the after effects of digestive disorders, however interestingly no such effects were observed from control group. Data analysis showed 0.24 risk ratio. The study outcomes helped to establish the idea that statins are not accountable for digestive disorders and the outcome nullify the delusion about that specific undesired effect of statins as that were only observed in diabetic patients since diabetes itself a metabolic and comorbid disorder blamed for aggravating the digestion.

 

Author Biographies

KIRAN RAFIQ, Jinnah Sindh Medical University, Karachi

Institute of Pharmaceutical Sciences, 

ZAFAR SAIED SAIFY, University of Karachi.

International Center of Chemical & Biological Sciences, 

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Published

2018-12-18

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