RISK FACTORS OF HYPOMAGNESEMIA IN PATIENTS WITH ACUTE ISCHEMIC STROKE (AIS): A CROSS SECTIONAL STUDY OF A TERTIARY CARE HOSPITAL, LAHORE PAKISTAN DURING 2015.

Abstract

Magnesium (Mg2+) has a very important role in maintaining both normal cellular and various body functions. Therefore, magnesium deficiency can pose adverse health effects including strokes. This study was aimed to determine the frequency of hypomagnesaemia in patients with acute ischemic stroke (AIS). A crosssectional study was carried out over a period of six months from during 2015 at the department of medicine, Services Hospital, Lahore. A total of 110 cases of AIS was included in the study and serum magnesium levels were determined including clinical information. The majority of the patients were between 61-70 years of age (43.6%). The 62 patients (56.4%) were male, and remaining 48 patients (43.6%) were female. The hypomagnesemia was found in 39 patients (35.5%). At the time of admission (at 24 hours) the mean serum Mg2+ concentration was found 1.5 mg/dl in acute ischemic patients. Among 39 hypomagnesemia patients, the majority (30%) were of age group 51-60 years. Among hypomagnesemia patients, the majority of the patients were male (38%) and nonsmokers (44%). The majority of hypomagnesemia patients was diagnosed with a history of diabetes (47%) and hypertension (44%). Most of the hypomagnesemia patients (53 %) were from middleclass. The hypomagnesemia patients (27%) were found malnutrition. There existed a significant difference in the following qualitative parameters: cigarette smoking, history of hypertension and malnutrition out of the total hypomagnesemia patients. The frequency of hypomagnesaemia in patients with stroke was 35.5%. Physicians should keep in mind that a high risk of hypomagnesemia exists and there is a need to recommend a Mg therapy.