PHYTOCHEMICAL SCREENING AND ANTIBACTERIAL EFFICACY OF BLACK CUMIN (NIGELLA SATIVA L.) SEEDS
Abstract
The use of medicinal plants against the treatment of many diseases is now widely under consideration and is being used as a secure choice for many diseases. Along with other medicinal plants, black cumin is most popular due to its traditional medicinal application. The main aim of this study was to perform phytochemical screening of black cumin in order to explore its potential against gram positive and negative strains of bacteria. Qualitative analysis of phytochemicals like tannins, terpenoids, anthocyanins, flavanoids, steroids, coumarins, leucoanthocyanins, cardiac glycosides, saponins and diterpenes were performed. Antimicrobial activity against gram positive and negative bacteria was investigated by using methanolic and aqueous extracts of black cumin. Phytochemical evaluation of both extracts confirmed the occurrence of flavonoids, alkaloid, phenol and tannins. Black cumin extract also exhibited the power as anti-microbial activity by inhibiting the growth of selected microbes. This study confirms the occurrence of vital phytochemicals in the extracts of black cumin seeds and thus can be concluded that seeds of black cumin can be used for the treatment of various diseases.