IN VITRO ANTIMICROBIAL AND ANTIOXIDANT ACTIVITIES OF TWO MEDICINAL PLANTS AGAINST SOME CLINICALLY IMPORTANT BACTERIA

Authors

  • FARZANA RASHID Lahore College for Women University, Lahore, Pakistan
  • FATIMA AMJAD BUTT Lahore College for Women University, Lahore, Pakistan
  • SOBIA NASREEN Lahore College for Women University, Lahore, Pakistan

Abstract

The aim of the present study was to evaluate the antimicrobial potential of Amaranthus viridis (Chowlai) and Cannabis sativa (Bhang) against clinically important bacteria, Staphylococcus aureus, Klebsiella pneumonia, Pseudomonas aeruginosa and Escherichia coli. The stem and leaf extracts of these plants were prepared in pure solvents, ethanol and methanol. Tetracycline was used as standard antibiotic for reference. Solvent extracts were screened for antimicrobial activities by disc diffusion method. The antioxidant activity was determined by 2,2-diphenyl-1-picrylhydazylhydrate (DPPH) method. A significantly high antimicrobial activity was observed in the ethanol leaf extracts of both plants with 13.8 to 21.33 mm zone of inhibition against S. aureus and K. pneumoniae. The study revealed that leaves of A. viridis and C. sativa possess broad spectrum antimicrobial activity and natural antioxidants that can be of considerable pharmaceutical importance.

Author Biographies

FARZANA RASHID, Lahore College for Women University, Lahore, Pakistan

Cell and Molecular Biology Laboratory, Dept. of Zoology, 

FATIMA AMJAD BUTT, Lahore College for Women University, Lahore, Pakistan

Cell and Molecular Biology Laboratory, Dept. of Zoology, 

SOBIA NASREEN, Lahore College for Women University, Lahore, Pakistan

Cell and Molecular Biology Laboratory, Dept. of Zoology, 

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Published

2021-04-13