BIOLOGICAL AND PHARMACOLOGICAL STUDIES OF HELIOTROPIUM DASYCARPUM LEDEB

Authors

  • TASEER AHMED BALOCH Department of Botany, University of Balochistan Quetta
  • SAADULLAH KHAN LEGHARI Department of Botany, University of Balochistan Quetta
  • MUHAMMAD SHAFI Department of Pharmacy University of Balochistan Quetta
  • MANZOOR IQBAL KHATTTAK Department of Chemistery University of Balochistan, Quetta
  • MUDASSIR ASRAR Department of Botany, University of Balochistan Quetta

Abstract

In this study, methanolic extract of Heliotropium dasycarpum was assessed to explored for its biological and pharmacological activities. For antibacterial, antifungal and phytotoxicity activities 11bacterial, 10 fungal and 4 weed plant species were used respectively. Plant showed inhibition zone against only 3 Bacterial (Chlamydia trachomatis, ?-hemolytic streptococci and Corynebacterium diphtheria) and four fungal species (Pneumocystis jiroveci, Cryptococcus neoformans, Zygomycetes and Microsporum canis) at maximum inhibitory concentration like; 60, 120 and 240 mg/ml and no inhibition zone was noted with minimum inhibitory concentration (MIC) of 10, 20 and 30 mg/ml. Phytochemical investigation exposed the occurrence of plant alkaloids, cardenolides, saponnins, flavonoids, enzymes, terpenoids and pigments. Results also indicated that H. dasycarpum had important phytotoxic activities. Plant designated maximum inhibition for the growth of Lemna minor L. (100 %) and Eichhornia crassipes (Mart.) Solms-laub. Maximun (75%) and minimum (20 % and 37 %) inhibition was noted for Elymus repens (L.) Gould and Convolvulus arvensis L. respectively

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Published

2019-06-03

Issue

Vol. 9 No. 1 (2019): Volume 9(1) June, 2019

Section

Articles

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