COMPLEX OF ?- SITOSTEROL WITH Co AT DIFFERENT MOLE RATIOS AND THEIR ANTIMICROBIAL ACTIVITIES

Abstract

The objective of the present work is to build up a plant-based method to reduce toxicity in our body which is caused due to high levels of some essential trace metals. Thus we undertook to investigate complex of ?Sitosterol with Co, at different mole ratio and their antimicrobial activities. Complexes of ?-sitosterol (?s-Co) were formed with Co, at mole ratios of (1:1) (1:2) and (1:3). By pH metric titrations complex formation has been determined. After the formation of complexes metals is unable to absorb in our body and are excreted out in the form of complex from our body. In vegetables most common plant phytosterol; ?-sitosterol is present. Through intake of vegetables toxic metal can form complex with ?-sitosterol and can be eliminated out from the body. Antimicrobial results indicate that all the complexes of ?s-Co have the potential to kill various types of fungi and bacteria, therefore these complexes may have the potential as therapeutic agents for the treatment of bacterial and fungal infections.