STARVATION INDUCED STRESS RESISTANCE IN MICE

Abstract

Starvation protects normal cells against toxicity stress but cancer cells which being mutated do not have protective mechanisms therefore stress results in death of cancer cells. In the present study we exposed normal and starved mice (24-36 hrs) to etoposide which induces oxidative stress. Starved mice remained physically healthy and active and they also gained weight while normal fed mice were lazy and there was only minor increase in weight as compared to starved mice. The present study provide evidence that the starvation has protective effects against stresses.