CIGARETTE SMOKING EFFECTS ON LIPID PROFILE

Abstract

The aim of this study was to determine the dyslipidemias in cigarette smokers of Karachi. This study was conducted at Federal Urdu University of Arts, Science and Technology (FUUAST) Gulshan-eIqbal campus Karachi and Abbassi Shaheed Hospital Karachi from Feb 2015 till Feb 2016. In this study 200 smokers and 200 non-smokers were included between age 18-45 years. Primary outcome measures were total cholesterol (TC), low density lipoprotein (LDL), triglyceride (TG) and high density lipoprotein (HDL). The mean TC, LDL and TG was 174.60 ± 24.46 mg/dl, 116.11 ± 13.0 mg/dl and 130.77 ± 19.62 mg/dL in smokers, respectively. It was significantly increased in smokers as compared to non smokers. While HDL was significantly decreased in smokers (32.51 ± 5.89). The p value for TC between smokers and nonsmokers group is <0.05, while for TG p value is <0.01. For LDL cholesterol p value is statistically significant <0.001. Cigarette smoking is associated with significant lower level of serum HDL and high level of TC, TG and LDL