STUDY OF LIPID PROFILE IN ALCOHOLIC AND NON-ALCOHOLIC INDIVIDUALS

Abstract

The aim of this study was to determine the Lipid profile in alcoholic males of Karachi. This study was conducted at Federal Urdu University of Arts, Science and Technology (FUUAST) Gulshan-e-Iqbal campus Karachi. In this study 100 alcoholic and 100 non-alcoholic persons were included between ages 26-45 years. Randomly selected volunteers were further divided in to four categories according to Body Mass Index (BMI), which was underweight, normal weight, overweight and obese. Primary outcome measures were total cholesterol (TC), low-density lipoprotein (LDL), triglyceride (TG) and high-density lipoprotein (HDL). The mean (19.1 ± 1.09) BMI of underweight control volunteers was significantly higher (P<0.001) than alcoholic persons (18.8 ± 0.09). Average BMI in normal weight (23.5 ± 6.5) volunteers was non-significantly higher as compare to alcoholic (22.01 ± 5.4) subjects. Mean BMI of overweight control (26.5 ± 8.5) subjects were significantly lower (P < 0.001) than alcoholic volunteers (27.8 ± 1.2). The average BMI in obese control (28.1 ± 3.9) subjects was significantly higher (P < 0.001) than alcoholic subjects (26.7 ± 2.3). The highest mean value of TC, TG, LDL and HDL was 34.2 ± 3.7 mg/dl, 37.7 ± 4.9 mg/dl, 33.8 ± 2.8 mg/dl and 41.2 ± 4.2 mg/dl in normal weight persons of Alcoholic group. The P value for TG and TC between alcoholic and non-alcoholic group is < 0.001. The LDL mean value is not found to be statistically significant between normal weight of control and study group. For HDL cholesterol P value is statistically significant <0.001.

Keywords: Alcoholic, Non- Alcoholic, Lipid profile, Overweight, Obese